CELL, MOLECULAR, AND DEVELOPMENTAL BIOLOGY GRADUATE PROGRAM

Subject abbreviation: CMDB College of Natural and Agricultural Sciences

Morris F. Maduro, Ph.D., Director Graduate Program, 1140 Batchelor Hall

• (800) 735-0717 or (951) 827-7378

cmdb.ucr.edu

Graduate Program Faculty

Professors Michael Adams, Ph.D. (Molecular, Cell and Systems Biology) Peter W. Atkinson, Ph.D. (Entomology) Julia Bailey-Serres, Ph.D. (Botany and Plant Sciences) Katherine Borkovich, Ph.D. (Microbiology and Plant Pathology) Richard Cardullo, Ph.D. (Evolution, Ecology, and Organismal Biology) Monica J. Carson, Ph.D. (School of Medicine) Xuemei Chen, Ph.D. (Botany and Plant Sciences) Shou-Wei Ding, Ph.D. (Microbiology and Plant Pathology) Iryna M. Ethell, Ph.D. (School of Medicine) Thomas Eulgem, Ph.D. (Botany and Plant Sciences) Brian Federici, Ph.D. (Entomology) Sarjeet S. Gill, Ph.D. (Molecular, Cell and Systems Biology) Venugopala Reddy Gonehal, Ph.D. (Botany and Plant Sciences) Hailing Jin, Ph.D. (Microbiology and Plant Pathology) Howard Judelson, Ph.D. (Microbiology and Plant Pathology) Isgouhi Kaloshian, Ph.D. (Nematology) Paul Larsen, Ph.D. (Biochemistry) Karine G. Le Roch, Ph.D. (Molecular, Cell and Systems Biology) Xuan Liu, Ph.D. (Biochemistry) David Lo, Ph.D., M.D. (School of Medicine) Wenbo Ma, Ph.D. (Microbiology and Plant Pathology) Morris F. Maduro, Ph.D. (Molecular, Cell and Systems Biology) Manuela Martins-Green, Ph.D. (Molecular, Cell and Systems Biology) Ernest Martinez, Ph.D. (Biochemistry) Dmitri Maslov, Ph.D. (Molecular, Cell and Systems Biology) Ashok Mulchandani, Ph.D. (Chemical Engineering) Michael Pirrung, Ph.D. President’s Chair (Chemistry) Alexander Raikhel (Entomology) A.L.N. Rao, Ph.D. (Microbiology and Plant Pathology) Anandasankar Ray, Ph.D. (Entomology) Frances Sladek, Ph.D. (Molecular, Cell and Systems Biology) Patricia S. Springer, Ph.D. (Botany and Plant Sciences) Prudence Talbot, Ph.D. (Molecular, Cell and Systems Biology) Linda L. Walling, Ph.D. (Botany and Plant Sciences) Yinsheng Wang, Ph.D. (Chemistry) Emma Wilson, Ph.D. (School of Medicine) Susan Wessler, Ph.D. (Botany and Plant Sciences) Shizhong Xu, Ph.D. (Botany and Plant Sciences) Zhenbiao Yang, Ph.D. (Botany and Plant Sciences) Changcheng Zhou, Ph.D. (School of Medicine) Raphael Zidovetzki, Ph.D. (Molecular, Cell and Systems Biology)

Associate Professors Jeffrey B. Bachant, Ph.D. (Molecular, Cell and Systems Biology) Meng Chen, Ph.D. (Botany and Plant Science) Djurdjica Coss, Ph.D. (School of Medicine) Margarita Currás-Collazo, Ph.D. (Molecular, Cell and Systems Biology) Anupama Dahanukar, Ph.D. (Entomology) Adler Dillman, Ph.D. (Nematology) Todd Fiacco, Ph.D. (Molecular, Cell and Systems Biology) Martin Garcia-Castro, Ph.D. (School of Medicine) Kaustabh Ghosh, Ph.D. (Bioengineering) Jiayu Liao, Ph.D. (Bioengineering) Huinan Liu, Ph.D. (Bioengineering) Amy Litt, Ph.D.(Botany and Plant Sciences) Christian Lytle, Ph.D. (School of Medicine) Meera Nair, Ph.D. (School of Medicine) Jin Nam, Ph.D. (Bioengineering) David Nelson, Ph.D. (Botany and Plant Sciences) Nicole zur Nieden, Ph.D. (Molecular, Cell and Systems Biology) James Ng, Ph.D. (Plant Pathology and Microbiology) Constance I. Nugent, Ph.D. (Molecular, Cell and Systems Biology) Carolyn Rasmussen, Ph.D. (Botany and Plant Sciences) Emma Wilson, Ph.D. (School of Medicine) Naoki Yamanaka, Ph.D. (Entomology)

Assistant Professors Garret Anderson, Ph.D. (Molecular, Cell and Systems Biology) Sihem Cheloufi, Ph.D. (Biochemistry) Qi Chen, Ph.D. (School of Medicine) Nicholas V. DiPatrizio, Ph.D. (School of Medicine) Jun-Hyeong Cho, Ph.D. (Molecular, Cell and Systems Biology) Patrick Degnan, Ph.D. (Plant Pathology and Microbiology) Juan Pablo Giraldo, Ph.D. (Botany and Plant Science) Weifeng Gu, Ph.D. (Molecular, Cell and Systems Biology) Rong Hai, Ph.D. (Microbiology and Plant Pathology) Sachiko Haga-Yamanaka, Ph.D. (Molecular, Cell and Systems Biology) Ansel Hsiao, Ph.D. (Plant Pathology and Microbiology) Ted Karginov, Ph.D. (Molecular, Cell and Systems Biology) Jiayu Liao, Ph.D. (Bioengineering) Huinan Liu, Ph.D. (Bioengineering) Kerry Mauck, Ph.D. (Entomology) Joshua Morgan, Ph.D. (Bioengineering) Jernej Murn, Ph.D. (Biochemistry) Dawn H. Nagel, Ph.D. (Botany and Plant Sciences) Tara Nordgren, Ph.D. (School of Medicine) Sean O’Leary, Ph.D. (Biochemistry) Martín Riccomagno, Ph.D. (Molecular, Cell and Systems Biology) Danelle Seymour, Ph.D. (Botany and Plant Sciences) Jefferson Perry, Ph.D. (Biochemistry) Jaimie Van Norman, Ph.D. (Botany and Plant Sciences) Hongdian Yang, Ph.D. (Molecular, Cell and Systems Biology) Sika Zheng, Ph.D. (School of Medicine)

The Cell, Molecular, and Developmental Biology Graduate Program is an interdepartmental program offering M.S. and Ph.D. degrees to students seeking advanced training in these disciplines. The program focuses on the bridge between basic and applied research and on the interface between cell, molecular, and develop- mental biology. Participating faculty are drawn from numerous biological sciences departments whose research interests in cell, molecular, and developmental biology span biomedical to agri- cultural problems, and students in the program benefit from unique training opportunities.

Students seeking admission into the program should meet all general requirements of the Graduate Division as printed in the Graduate Studies section of this catalog.

The Cell, Molecular, and Developmental Biology program offers the M.S. and Ph.D. degrees in Cell, Molecular, and Developmental Biology.

Admission Applicants should have adequate undergraduate course work in chemistry (two years), physics (one year), calculus (one year), statistics (one course), biochemistry (one course), and biology (two years, including a course in genetics and two courses among cell, molecular, or develop- mental biology). Applicants with strong academ- ic records but with deficiencies in preparation for graduate training may be admitted and must rectify undergraduate deficiencies early in the first two years of residence. Applicants must submit GRE General Test scores (verbal, quanti- tative and analytical).

Course Work All students must complete the following core of course work:

• 1. CMDB 203

• 2. One graduate-level course in cell biology

(BIOL 200/CMDB 200, BPSC 237, or NRSC 200A/PSYC 200A)

• 3. One graduate-level course in molecular

biology (BIOL 201/CMDB 201, BCH 211, BPSC 231/BCH 231, BMSC 202, or NRSC 200B/PSYC 200B)

• 4. One graduate-level course in developmental

biology (BPSC 232, CMDB 202)

• 5. GDIV 403 Research and Scholarship Ethics

(1 unit; may be taken any time prior to graduation)

Each student must enroll in the program semi- nars (CMDB 257, CMDB 258) each time they are offered. Upon entry into the program, each stu- dent meets with a guidance committee, which recommends a course of study commensurate with the student’s interests and background.

The Cell, Molecular, and Developmental Biology program offers an M.S. degree.

Plan I (Thesis) Students complete the course work above, enroll in one graduate seminar course in cell, molecular, or developmental biology (SCH 230(E-Z), BIOL 281(E-Z)/CMDB 281(E-Z), BPSC 240, BCH 289/BIOL 289/NRSC 289/PSYC 289) or other with consent of the graduate advisor, and undertake a research project leading to a thesis.

Each student must complete 36 units of course work, of which at least 24 units must be in the graduate series (200 level) in the biological sciences. No more than 12 units in courses numbered 290-299 may be taken to fulfill the 24-unit requirement. Candidates for the M.S. degree must defend their thesis at a public oral presentation.

Normative Time to Degree Two years

The Cell, Molecular, and Developmental Biology program offers a Ph.D. degree.

• 1. Completion of the course work listed above

• 2. One additional graduate course in cell,

molecular, and developmental biology

• 3. One graduate seminar course in cell,

molecular, or developmental biology (SCH 230 (E-Z), BIOL 281 (E-Z)/CMDB 281 (EZ), BPSC 240, SCH 289/BIOL 289/CHEM 289/ENTM 289/NRSC 289/PSYC 289} or other with consent of the graduate advisor

• 4. A research project leading to a dissertation

• 5. Oral public defense of dissertation

Written and Oral Qualifying Examinations Doctoral students are advanced to candidacy following successful completion of written and oral qualifying examinations. Students write a proposal detailing the rationale, specific aims, and approaches to be undertaken for their pro- posed dissertation research prior to taking the oral qualifying examination.

Professional Development Training Ph.D. graduate students fulfill their professional development training requirement through the following activities:

• 1) Responsible conduction of research:

One-time mandatory enrollment in GDIV 403 Research and Scholarship Ethics (1 unit; may be taken any time prior to graduation).

• 2) Teaching: One-time mandatory orientation

in the Teaching Assistant Development Program administered through Graduate Division (must be fulfilled prior to classroom instruction). CMDB requires two quarters of TA teaching.

• 3) Safety training: Mandatory laborato-

ry safety training administered through Environmental Health and Safety. Addi- tional training may be mandated for some research activities.

• 4) Presentations, scientific interactions

and intellectual development: Enrollment each quarter in CMDB 257 Seminar in Cell, Molecular and Developmental Biology. Part of the professional development in this course involves luncheon meetings be- tween the speakers and students following the seminar. CMDB also offers opportu- nities for participation and presentation in intra-mural research seminars.

• 5) Research Training: Individual research

training in major professor laboratories is associated with enrollment in CMDB 250, which encompasses laboratory journal clubs and lab meetings, as well as CMDB 297 and CMDB 299 research units. Students are also required to schedule an Annual Research Progress Evaluation (ARPE) with their guidance or dissertation committee to monitor ongoing professional development.

Dissertation Candidates must successfully defend their dis- sertation research in a public oral presentation.

Teaching Requirement Students must fulfill a two-quarter teaching requirement.

There is a high demand in industry and academia for scientists with training in cell, molecular, and developmental biology. Students matriculating from the program are well trained in this field and successfully obtain positions in biotechnology, including biomedical and agricultural industries, and at colleges and universities nationwide.

Normative Time to Degree Five years