BIOPHYSICS

Subject abbreviation: BPHY See schedule of classes for courses

College of Natural and Agricultural Sciences Russ Hille, Ph.D., Program Director Program Office: 1140 Batchelor Hall

• (800) 735-0717 or (951) 827-6746

biophysics.ucr.edu

Professors Mark Alber, Ph.D. Distinguished Mathematics Bahman Anvari, Ph.D. Bioengineering Richard Cardullo, Ph.D. Evolution, Ecology, and Organismal Biology Chia en Chang, Ph.D. Chemistry Richard Debus, Ph.D. Biochemistry Theodore Garland, Jr., Ph.D. Distinguished Evolution, Ecology, and Organismal Biology Adam Godzik, Ph.D. Biomedical Sciences Russ Hille, Ph.D. Distinguished Biochemistry Richard Hooley, Ph.D. Chemistry Darrel Jenerette, Ph.D. Botany and Plant Sciences Ryan Julian, Ph.D. Chemistry Umar Mohideen, Ph.D. Physics and Astronomy Leonard Mueller, Ph.D. Chemistry Maurizio Pellucchia, Ph.D. Biomedical Sciences Louis Santiago, Ph.D. Botany and Plant Sciences Yinsheng Wang, Ph.D. Chemistry Roya Zandi, Ph.D. Physics and Astronomy Wenwan Zhong, Ph.D. Chemistry

Associate Professors Li Fan, Ph.D. Biochemistry Jikui Song, Ph.D. Biochemistry

Assistant Professors John Barton, Ph.D. Physics and Astronomy Gregor Blaha, Ph.D. Biochemistry Joseph Genereux, Ph.D. Chemistry Thomas Kuhlman, Ph.D. Physics and Astronomy Sean O’Leary, Ph.D. Biochemistry John Jefferson Perry, Ph.D. Biochemistry Nicole Rafferty, Ph.D. Evolution, Ecology, and Organismal Biology Min Xue, Ph.D. Chemistry

The program offers the M.S. and Ph.D. degree in Biophysics.

The interdepartmental graduate program in Biophysics has participating faculty from the departments of Biochemistry; Bioengineer- ing; Biomedical Sciences; Botany and Plant Sciences; Chemistry; Evolution, Ecology and Organismal Biology; Mathematics; and Physics and Astronomy.

The goal of the program is to promote teaching, training and research in the field of Biophysics. Areas of specialization include biological electron transfer, computational/mathematical model- ing of biological systems, structural biology, neurobiophysics, imaging and protein engineer- ing. Biophysicists are needed by institutions of higher learning, and by federal, state and private research organizations.

Admission Students must have a B.A. or B.S. degree in Biology, Biochemistry, Biophysics, Chemistry, Physics or in a related field from an accredited institution and an academic record that satisfies the minimum admission standards established by the UCR Graduate Division. In addition, stu- dents are required to take the GRE General Test as well as the Subject Examination in Biochem- istry, Biology, Chemistry or Physics, which must be submitted at the time of application. Students admitted to regular standing will have satisfied all prerequisite course work. Under special cir- cumstances, students who have not completed all undergraduate requirements may be admitted provided that the deficiencies are corrected early in their graduate studies. Undergraduate or other previous training must include the following coursework:

• • One year of introductory biochemistry,

including laboratory

• • One year of introductory biology, including

laboratory

• • One year of introductory chemistry, including

laboratory

• • One year of organic chemistry, including

laboratory

• • One year of introductory physics, including

laboratory

• • One year of calculus, plus one upper

division mathematics course

Students with strong academic records may be admitted with coursework deficiencies, provided they are remediated during the first two years of graduate study.

The program offers the Ph.D. degree in Biophysics.

Course Work Thirty-six (36) units of 100 or 200 series courses, of which at least twenty-four (24) units must be in the graduate 200 series; includes the program’s graduate core curriculum and courses from a list of approved electives. A minimum of sixteen (16) units of coursework other than courses in the 290 series must be completed in fulfillment of the twenty-four (24) unit program requirement for graduate coursework.

All students are required to take a sequence of core courses (BCH 184, BCH 210, BIOL 203, and PHYS 246) in their first year, and complete a series of research rotations in laboratories of participating faculty under BPHY 297 as part of the thesis advisor selection process. Participa- tion in the Biophysics Graduate Seminar (BPHY 252) is also required for each quarter the student is enrolled; each student is expected to present a formal research seminar in this course prior to graduation. Students who present will receive a letter grade.

Approved Elective Courses include: BCH 186, BCH 187, BCH 230F, BIEN 135, BIEN 142, BIEN 160, BIEN 165, BIEN 242, BIEN 245, BIEN 249, BIEN 251, CHEM 201A, CHEM 201B, CHEM 201C, CHEM 201D, CHEM 201E, CHEM 206A, CHEM 206B, CHEM 209M, CHEM 211D, CHEM 229Q, PHYS 145A, PHYS 145B, PHYS 145C, PHYS 212A, PHYS 212B

Comprehensive Examination At the end of the first year, and no later than the end of the second year, students must pass a written comprehensive examination consisting of questions provided by the participating faculty, with topics taken from the core curriculum.

Qualifying Examination and Advancement to Candidacy Doctoral students must pass a written qualifying examination that will consist of the preparation of a research proposal based on their dis- sertation work and taking the form of a grant application to the National Science Founda- tion or National Institutes of Health. Once the proposal is deemed satisfactory, the student must pass an oral examination that will consist of a defense of the written research proposal before the student’s qualifying exam committee. Upon successful completion of all coursework and passing of the Qualifying Examination, the student will advance to candidacy.

Dissertation Students are expected to complete laboratory rotations and select a dissertation advisor by the end of their first academic year. The dissertation advisor will chair a Ph.D. Dissertation Committee that will meet annually to assess progress and provide input to the research project. A written dissertation will be completed by each student in the program.

Final Defense Doctoral candidates will defend their disserta- tions in a public oral presentation at a time an- nounced to members of the University commu- nity. The Dissertation Committee will then make a recommendation to the Graduate Division as to whether the degree of Ph.D. be conferred.

Professional Development Biophysics students must complete an annual research evaluation, complete a minimum of 2 quarters as a teaching assistant, and complete GDIV 403.

Normative Time to Degree 15 quarters

The program offers the M.S. degree in Biophysics.

Students will normally be admitted to the Ph.D. program. Upon advancement to candidacy for the Ph.D. degree the student may petition the Graduate Division for conferral of the M.S. degree.

Students enrolling in the master’s degree in Biophysics must meet the requirements for the Plan II of the UCR Graduate Council, take core courses as described above and pass a Comprehensive Examination.

Plan II (Comprehensive Exam) Thirty-six (36) units of 100 or 200 series courses, of which at least eighteen (18) units must be in the graduate 200 series; includes the program’s graduate core curriculum and courses from a list of approved electives. Students must enroll in BPHY 252 each quarter offered. Students must pass a three-hour Comprehensive Examina- tion consisting of questions provided by the participating faculty, with topics taken from the core-curriculum.

Professional Development Biophysics students must complete GDIV 403.

Normative Time to Degree 6 quarters