Prerequisites: BCH 100 with a grade of “C-” or better or BCH 110A or BCH 110HA with a grade of “C-” or better; BIEN 135 with grade of “C-” or better, or CHEM 109 with grade of “C-” or better or CHEM 110A with grade of “C-” or better; or consent of instructor
Description: Explores modern biophysical methods determining the structures of biological macromolecules and relating structure to function. Covers x-ray crystallography, NMR, and cryoelectron microscopy. Addresses imaging and mass spectrometry for determining structure and ultraviolet, visible, infrared, RAMAN, fluorescence, NMR, EPR, and other forms of spectroscopy for relating macromolecular structure to function.