Prerequisites: BIOL 102, CHEM 112C, or equivalents; a passing grade on the Chemistry Department organic orientation examination
Description: Explores topics in chemical genomics. Part I of the course involves combinatorial principles, library methods, solid-phase and split-pool synthesis, deconvolution, library design and informatics, and parallel synthesis. Part II involves screening and selection systems, forward and reverse chemical genetic approaches, phenocopies and epistasis, preparation and use of molecular arrays, and target identification.
Credit: May be taken Satisfactory (S) or No Credit (NC) with consent of instructor and graduate advisor.