Prerequisites: BIOL 102, CHEM 112C, or equivalents; a passing grade on the Chemistry Department organic orientation exami- nation
Description: Explores topics in chemical genomics. Part I of the course involves combinatorial principles, library methods, solid-phase and split-pool synthesis, decon- volution, library design and informatics, and parallel synthesis. Part II involves screening and selection sys- tems, forward and reverse chemical genetic approaches, phenocopies and epistasis, preparation and use of molecular arrays, and target identification.
Credit: May be taken Satisfactory (S) or No Credit (NC) with consent of instructor and graduate advisor.